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I'm aligning a short sequence to a very long one, and they look like
ATATA
ATATATATATA<...>A
When I align them with abpoa, it puts the gap in the middle
ATAT------------<...>A
ATATATATATA<...>A
But I'd much rather have an alignment like
ATATA-----------<...>
ATATATATATA<....>
I can understand that, strictly speaking, with the global alignment scoring model, there isn't much difference between these two scenarios, in practice I think the second one is always preferred. Do you think it would be possible to add some way to left shift or favour gaps at the ends in global alignment mode?
I'm aligning a short sequence to a very long one, and they look like
When I align them with abpoa, it puts the gap in the middle
But I'd much rather have an alignment like
I can understand that, strictly speaking, with the global alignment scoring model, there isn't much difference between these two scenarios, in practice I think the second one is always preferred. Do you think it would be possible to add some way to left shift or favour gaps at the ends in global alignment mode?
Thanks, as always.
to reproduce
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