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原文:(E) Density plots showing the distribution of T cells (upper panels) or expanded T cells (middle and lower panels) along the CD4+ Th1, CD8+ Tex, and Trm trajectories, as calculated by Slingshot, while stratifying for treatment arm (upper panels) or sample type (middle and lower panels). The overlapping area between treatment arms is gray. Differences in distributions were calculated by the KS.test (see STAR Methods). Tn/cm, naive/central-memory T cell; Tem, effector/memory T cell; Th1, T helper 1 cell; Th17, T helper 17 cell; Tfh, follicular helper T cell; Treg, regulatory T cell; Temra, effector-memory re-expressing CD45RA T cell; Tex, exhausted T cell; Trm, tissue-resident memory T cell; NKinfla, inflammatory natural killer cell; NKcyto, cytotoxic natural killer cell.