diff --git a/.github/workflows/nodejs.yml b/.github/workflows/nodejs.yml
index 58149df628a..a6b43d87869 100644
--- a/.github/workflows/nodejs.yml
+++ b/.github/workflows/nodejs.yml
@@ -141,6 +141,77 @@ jobs:
       - name: Run tests
         run: npm run test:javascript:without-intl
 
+  test-without-ssl:
+    name: Test with Node.js ${{ matrix.version }} compiled --without-ssl
+    strategy:
+      fail-fast: false
+      max-parallel: 0
+      matrix:
+        version: [22]
+    runs-on: ubuntu-latest
+    timeout-minutes: 120
+    steps:
+      - name: Checkout
+        uses: actions/checkout@9bb56186c3b09b4f86b1c65136769dd318469633 # v4.1.2
+        with:
+          persist-credentials: false
+
+      # Setup node, install deps, and build undici prior to building icu-less node and testing
+      - name: Setup Node.js@${{ inputs.version }}
+        uses: actions/setup-node@60edb5dd545a775178f52524783378180af0d1f8 # v4.0.2
+        with:
+          node-version: ${{ inputs.version }}
+
+      - name: Install dependencies
+        run: npm install
+
+      - name: Build undici
+        run: npm run build:node
+
+      - name: Determine latest release
+        id: release
+        uses: actions/github-script@60a0d83039c74a4aee543508d2ffcb1c3799cdea # v7.0.1
+        with:
+          result-encoding: string
+          script: |
+            const req = await fetch('https://nodejs.org/download/release/index.json')
+            const releases = await req.json()
+
+            const latest = releases.find((r) => r.version.startsWith('v${{ matrix.version }}'))
+            return latest.version
+
+      - name: Download and extract source
+        run: curl https://nodejs.org/download/release/${{ steps.release.outputs.result }}/node-${{ steps.release.outputs.result }}.tar.xz | tar xfJ -
+
+      - name: Install ninja
+        run: sudo apt-get install ninja-build
+
+      - name: ccache
+        uses: hendrikmuhs/ccache-action@ed74d11c0b343532753ecead8a951bb09bb34bc9 #v1.2.14
+        with:
+          key: node${{ matrix.version }}
+
+      - name: Build node
+        working-directory: ./node-${{ steps.release.outputs.result }}
+        run: |
+          export CC="ccache gcc"
+          export CXX="ccache g++"
+          ./configure --without-ssl --ninja --prefix=./final
+          make
+          make install
+          echo "$(pwd)/final/bin" >> $GITHUB_PATH
+
+      - name: Print version information
+        run: |
+          echo OS: $(node -p "os.version()")
+          echo Node.js: $(node --version)
+          echo npm: $(npm --version)
+          echo git: $(git --version)
+          echo icu config: $(node -e "console.log(process.config)" | grep icu)
+
+      - name: Run tests
+        run: npm run test:javascript
+
   test-fuzzing:
     name: Fuzzing
     runs-on: ubuntu-latest