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improve phase block #124

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LGG02 opened this issue Apr 25, 2024 · 1 comment
Open

improve phase block #124

LGG02 opened this issue Apr 25, 2024 · 1 comment

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@LGG02
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LGG02 commented Apr 25, 2024

Hi @arangrhie
Thank you and the team for great QC tool. I have two questions:

  1. I have parental data from HiFi and MGI platform. I used HiFi parental data and MGI for assessment. HiFi based phasing results shows very high phaseblock N50 while MGI shows less
    phase_block

  2. From the phased_block.bed, we know the position where the switch are, any guidance on how to fix?

thank you for your valuable insights

@arangrhie
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Hi @LGG02,

Are you assessing the homopolymer compressed assembly for both platforms? Your HiFi uses paternal_compress.k31.hapmer. Can you re-plot them using non-compressed assembly with regular (not compressed) hapmers?

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