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Most chimpanzee centromeres that are acrocentric appear telocentric in Ideogram.js.
Specifically, chimpanzee chromosomes 13, 14, 15, and 22 are acrocentric like their human orthologs, but appear telocentric like mouse chromosomes. The only acrocentric chimpanzee chromosome that is properly rendered as such is chromosome Y.
Below is what the chimpanzee genome looks like in Ideogram.js. Note the centromere positions of chromosomes 13, 14, 15, and 22.
The cause of this issue may be related to Ideogram using Pan_tro_3.0 (panTro5, GCF_000001515.7) as its default chimpanzee genome assembly, whereas the above screenshot of NCBI GDP uses Pan_troglodytes-2.1.4 (panTro4, GCF_000001515.6). GDP has some apparent flaws -- e.g. chr2B is much smaller than shown.
The best available reference for chimpanzee cytogenetics seems to be Yunis, J. & Prakash, O. The origin of man: a chromosomal pictorial legacy. Science 215, 1525–1530 (1982). A figure from that paper shows banded chromosomes of human, chimpanzee, gorilla, and orangutan:
Fix this issue with chimpanzee centromere positioning, using NCBI GDP and Yunis and Prakesh (1982) as guidance.
The text was updated successfully, but these errors were encountered:
Most chimpanzee centromeres that are acrocentric appear telocentric in Ideogram.js.
Specifically, chimpanzee chromosomes 13, 14, 15, and 22 are acrocentric like their human orthologs, but appear telocentric like mouse chromosomes. The only acrocentric chimpanzee chromosome that is properly rendered as such is chromosome Y.
Below is what the chimpanzee genome looks like in Ideogram.js. Note the centromere positions of chromosomes 13, 14, 15, and 22.
And here is how chimpanzee looks in NCBI Genome Decoration Page (GDP):
The cause of this issue may be related to Ideogram using Pan_tro_3.0 (panTro5, GCF_000001515.7) as its default chimpanzee genome assembly, whereas the above screenshot of NCBI GDP uses Pan_troglodytes-2.1.4 (panTro4, GCF_000001515.6). GDP has some apparent flaws -- e.g. chr2B is much smaller than shown.
The best available reference for chimpanzee cytogenetics seems to be Yunis, J. & Prakash, O. The origin of man: a chromosomal pictorial legacy. Science 215, 1525–1530 (1982). A figure from that paper shows banded chromosomes of human, chimpanzee, gorilla, and orangutan:
Fix this issue with chimpanzee centromere positioning, using NCBI GDP and Yunis and Prakesh (1982) as guidance.
The text was updated successfully, but these errors were encountered: